Kisspeptin-10
Kisspeptin-10 is a biologically active fragment of the kisspeptin protein studied for its role in reproductive axis signaling and gonadotropin regulation pathways [1,2].
This peptide is for research purposes only. Not for human consumption.
Description
GnRH Pathway Interaction
Kisspeptin-10 is examined for its ability to activate kisspeptin receptors (KISS1R), which are upstream regulators of gonadotropin-releasing hormone signaling [1]. Research focuses on receptor activation dynamics and downstream neuroendocrine signaling.
Neuroendocrine Regulation
Studies investigate how kisspeptin fragments influence hypothalamic signaling, luteinizing hormone release patterns, and reproductive axis coordination [2]. These models help clarify signaling hierarchy within endocrine networks.
Fragment-Based Signaling Studies
As a shorter active fragment, Kisspeptin-10 is frequently used to study potency, receptor affinity, and signaling efficiency compared to longer kisspeptin sequences [1].
Key Specs
- Peptide class: kisspeptin fragment
- Research context: reproductive and neuroendocrine signaling
- References: PubChem, PubMed [1,2]
Referenced Citations
- PubChem, Kisspeptin-10: https://pubchem.ncbi.nlm.nih.gov/compound/Kisspeptin-10
- PubMed, Kisspeptin signaling and GnRH regulation: https://pubmed.ncbi.nlm.nih.gov/15004014/
GnRH Pathway Interaction
Kisspeptin-10 is examined for its ability to activate kisspeptin receptors (KISS1R), which are upstream regulators of gonadotropin-releasing hormone signaling [1]. Research focuses on receptor activation dynamics and downstream neuroendocrine signaling.
Neuroendocrine Regulation
Studies investigate how kisspeptin fragments influence hypothalamic signaling, luteinizing hormone release patterns, and reproductive axis coordination [2]. These models help clarify signaling hierarchy within endocrine networks.
Fragment-Based Signaling Studies
As a shorter active fragment, Kisspeptin-10 is frequently used to study potency, receptor affinity, and signaling efficiency compared to longer kisspeptin sequences [1].
Key Specs
- Peptide class: kisspeptin fragment
- Research context: reproductive and neuroendocrine signaling
- References: PubChem, PubMed [1,2]
Referenced Citations
- PubChem, Kisspeptin-10: https://pubchem.ncbi.nlm.nih.gov/compound/Kisspeptin-10
- PubMed, Kisspeptin signaling and GnRH regulation: https://pubmed.ncbi.nlm.nih.gov/15004014/
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